Berntorp, E. et al. Haemophilia. Nat. Reviews Disease Primers. 7 (1), 45 (2021).
Peyvandi, F., Garagiola, I. & Young, G. The past and future of haemophilia: diagnosis, treatments, and its complications. Lancet (London England). 388 (10040), 187–197 (2016).
Gualtierotti, R., Solimeno, L. P. & Peyvandi, F. Hemophilic arthropathy: current knowledge and future perspectives. J. Thromb. Haemost. 19 (9), 2112–2121 (2021).
Beckers, G., Masse, V., Vendittoli, P. A. & Morcos, M. W. Primary total knee arthroplasty in hemophilic arthropathy. EFORT Open. Rev. 8 (11), 830–840 (2023).
Rodriguez-Merchan, E. C. Serological biomarkers in hemophilic arthropathy: can they be used to monitor bleeding and ongoing progression of blood-induced joint disease in patients with hemophilia? Blood Rev. 41, 100642 (2020).
Verhagen, M. J. A. et al. Patients with moderate hemophilia A and B with a severe bleeding phenotype have an increased burden of disease. J. Thromb. Haemost. 22 (1), 152–162 (2024).
Rehill, A. M., McCluskey, S., O’Donnell, J. S., Dockal, M. & Preston, R. J. S. Heterogeneity in bleeding tendency and arthropathy development in individuals with hemophilia. Semin. Thromb. Hemost. 47 (2), 183–191 (2021).
Kleiboer, B. et al. Postoperative bleeding complications in patients with hemophilia undergoing major orthopedic surgery: A prospective multicenter observational study. J. Thromb. Haemost. 20 (4), 857–865 (2022).
Beckers, G. et al. Clinical outcomes of total knee arthroplasty in patients who have hemophilic arthropathy: A prospective study. J. Arthroplast. 40 (1), 102–110 (2025).
Rodriguez-Merchan, E. C. et al. Total knee arthroplasty in hemophilia: lessons learned and projections of what’s next for hemophilic knee joint health. Expert Rev. Hematol. 15 (1), 65–82 (2022).
Rodriguez-Merchan, E. C. Primary total knee arthroplasty in hemophilia and allied disorders: revision rates and their causes. Archives Bone Joint Surg. 12 (6), 428–432 (2024).
Chai, X., Liu, H., You, C. & Wang, C. Efficacy of additional corticosteroid in a multimodal cocktail for postoperative analgesia following total knee arthroplasty: A Meta-Analysis of randomized controlled trials. Pain Pract. 19 (3), 316–327 (2019).
Andersen, K. V. et al. Local infiltration analgesia is not improved by postoperative intra-articular bolus injections for pain after total hip arthroplasty. Acta Orthop. 86 (6), 647–653 (2015).
Barrington, J. W., Lovald, S. T., Ong, K. L., Watson, H. N. & Emerson, R. H. Jr. Postoperative pain after primary total knee arthroplasty: comparison of local injection analgesic cocktails and the role of demographic and surgical factors. J. Arthroplast. 31 (9 Suppl), 288–292 (2016).
Li, D., Tan, Z., Kang, P., Shen, B. & Pei, F. Effects of multi-site infiltration analgesia on pain management and early rehabilitation compared with femoral nerve or adductor Canal block for patients undergoing total knee arthroplasty: a prospective randomized controlled trial. Int. Orthop. 41 (1), 75–83 (2017).
Dalury, D. F., Lieberman, J. R. & MacDonald, S. J. Current and innovative pain management techniques in total knee arthroplasty. J. Bone Joint Surg. Am. Volume. 93 (20), 1938–1943 (2011).
Motififard, M., Omidian, A. & Badiei, S. Pre-emptive injection of peri-articular-multimodal drug for post-operative pain management in total knee arthroplasty: a double-blind randomized clinical trial. Int. Orthop. 41 (5), 939–947 (2017).
Joo, J. H., Park, J. W., Kim, J. S. & Kim, Y. H. Is intra-articular multimodal drug injection effective in pain management after total knee arthroplasty? A randomized, double-blinded, prospective study. J. Arthroplast. 26 (7), 1095–1099 (2011).
Collaborators, D. T. & West Midlands Research, C. Dexamethasone versus standard treatment for postoperative nausea and vomiting in Gastrointestinal surgery: randomised controlled trial (DREAMS Trial). BMJ 357, j1455 (2017).
Li, D., Wang, C., Yang, Z. & Kang, P. Effect of intravenous corticosteroids on pain management and early rehabilitation in patients undergoing total knee or hip arthroplasty: A Meta-Analysis of randomized controlled trials. Pain Pract. 18 (4), 487–499 (2018).
Ranawat, A. S. & Ranawat, C. S. Pain management and accelerated rehabilitation for total hip and total knee arthroplasty. J. Arthroplast. 22 (7 Suppl 3), 12–15 (2007).
Wang, R. et al. Total knee arthroplasty in patients with haemophilic arthropathy is effective and safe according to the outcomes at a mid-term follow-up. J. Orthop. Traumatol. 23 (1), 31 (2022).
Sadigursky, D. et al. LOCAL PERIARTICULAR ANALGESIA IN TOTAL KNEE ARTHROPLASTY. Acta Ortopedica Brasileira. 25 (2), 81–84 (2017).
de Ladoucette, A. Management of perioperative pain after TKA. Orthop. Traumatol. Surg. Res. 109 (1S), 103443 (2023).
Li, J. W., Ma, Y. S. & Xiao, L. K. Postoperative pain management in total knee arthroplasty. Orthop. Surg. 11 (5), 755–761 (2019).
Bernucci, F. & Carli, F. Functional outcome after major orthopedic surgery: the role of regional anesthesia redefined. Curr. Opin. Anaesthesiol. 25 (5), 621–628 (2012).
Hollmann, M. W. & Durieux, M. E. Local anesthetics and the inflammatory response: a new therapeutic indication?. Anesthesiology 93(3), 858–875 (2000).
Wu, L. et al. The optimal dosage, route and timing of glucocorticoids administration for improving knee function, pain and inflammation in primary total knee arthroplasty: A systematic review and network meta-analysis of 34 randomized trials. Int. J. Surg. (London England). 82, 182–191 (2020).
Grosu, I., Lavand’homme, P. & Thienpont, E. Pain after knee arthroplasty: an unresolved issue. Knee Surg. Sports Traumatol. Arthrosc. 22 (8), 1744–1758 (2014).
Oshima, A. et al. The comparison of dexamethasone and triamcinolone periarticular administration in total knee arthroplasty: retrospective cohort study. BMC Musculoskelet. Disord. 23 (1), 120 (2022).
Andres, B. M., Taub, D. D., Gurkan, I. & Wenz, J. F. Postoperative fever after total knee arthroplasty: the role of cytokines. Clin. Orthop. Relat. Res. 2003(415), 221–231 (2003).
Chavez, M. A. et al. Length of stay and trauma center finances: A disparity of payer source at a level I trauma center. J. Trauma. Acute Care Surg. 92 (4), 683–690 (2022).
Wohlgemut, J. M., Ramsay, G., Boyers, D. & Jansen, J. O. Current and projected financial burden of emergency general surgery for adults in Scotland’s single payer healthcare system: A cost analysis of hospital admissions. Ann. Surg. 274 (6), e522–e528 (2021).